aminoacyl tRNA

aminoacyl tRNA

[ə¦mē·nō¦as·əl ¦tē‚är‚en′ā]
(cell and molecular biology)
A molecular complex formed during protein synthesis by the linkage of a transfer ribonucleic acid molecule (tRNA) with its corresponding amino acid.
References in periodicals archive ?
One such family of enzymes is the aminoacyl tRNA synthetase, which is responsible for catalyzing the reaction that "charges" transfer-RNA with an amino acid.
org/content/early/2016/11/23/1617316113) discovered an aminoacyl tRNA synthetase called AlaRS that lacks any new decorations and can somehow still carry out its new role in humans without overhauling its basic architecture.
The RNA components of a ribosome are working like a ribozyme and play a central role, together with aminoacyl tRNA, in polypeptide formation, while the ribosomal proteins maintain the ribosomal structure and regulate the translational process.
Physiocrines are derived from aminoacyl tRNA synthetases, which have been known for decades to function intracellularly in protein synthesis.
The privately held biotech was founded by Scripps Research Institute Professor Paul Schimmel, a leading aminoacyl tRNA synthetase scientist, and is backed by top life sciences investors Alta Partners, Cardinal Partners, Domain Associates and Polaris Ventures.
ribosomes, ribosomal proteins, aminoacyl tRNA synthetases) of developing embryos of S.
Chapter 4 presents the two subclasses of aminoacyl tRNA synthetases and the significance of the genetic code assignments to each enzyme.
The top-half domain, sometimes referred to as a tRNA "minihelix," has been shown to provide the determinants necessary for specific charging by aminoacyl tRNA synthetases (14, 15); for interaction with elongation factor Tu (16); for 5[prime] processing by RNase P (17); and for distinguishing elongator from initiator tRNA (18).
Consequently I don't think that a full complement of aminoacyl tRNAs could be made by ribozymes.