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aminopterin

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.27 sec.
aminopterin: see metabolite metabolite, organic compound that is a starting material in, an intermediate in, or an end product of metabolism . Starting materials are substances, usually small and of simple structure, absorbed by the organism as food.
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* In utero exposure to aminopterin, an antagonist of folic acid, has been associated with anencephaly, meningocele, hydrocephalus, and cleft lip and palate (Thiersch 1952; Warkany et al.
Talotrexin is a novel, non-classical antifolate that is a water-soluble, non-polyglutamatable analogue of aminopterin.
-- Discontinuation of the development of aminopterin, an
 
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