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amyloid |
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amyloid [′am·ə‚lȯid] (pathology) An abnormal protein deposited in tissues, formed from the infiltration of an unknown substance, probably a carbohydrate. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Specifically, using DNAVEC's proprietary Sendai virus vector,
they plan to develop a gene vaccine that can selectively induce the
production of anti-beta amyloid antibodies. Amyloidosis is characterized by an abnormal extracellular
deposition of amyloid in different tissues and organs, where it usually
causes some type of dysfunction. Neutralization of transthyretin reverses the neuroprotective
effects of secreted amyloid precursor protein (APP) in APPSW mice
resulting in tau phosphorylation and loss of hippocampal neurons:
support for the amyloid hypothesis. |
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