amyloid


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Related to amyloid: Amyloid angiopathy, Amyloid precursor protein

amyloid

[′am·ə‚lȯid]
(pathology)
An abnormal protein deposited in tissues, formed from the infiltration of an unknown substance, probably a carbohydrate.
References in periodicals archive ?
In addition to altering patient diagnosis, results showed that knowledge of amyloid status as determined by florbetapir imaging changed patient management in the majority of study patients, particularly Alzheimer's disease medications (cholinesterase inhibitor use), in a direction consistent with amyloid status.
Therefore, we conducted an individual participant meta-analysis to estimate the prevalence of amyloid positivity in a large sample encompassing a variety of dementia syndromes," wrote Rik Ossenkoppele, Ph.
To find out if amyloids can behave like enzymes too, Korendovych and his team designed seven simple peptides that were made from seven amino acids.
The biosensor works by producing an electrical signal on detecting amyloid clusters in the blood.
Wake time after sleep onset also was significantly higher (worse) among subjects with a strong likelihood of amyloid deposition than it was among those without it (63.
For patients from the four separate biopsy studies 18F flutemetamol detected beta amyloid with a median sensitivity ranging from 75-100 percent and specificity ranging from 99-100 percent.
It has been established in earlier studies that low density lipoprotein receptor related protein (LRP) acts as a chaperone in transporting beta amyloid from the brain into the periphery.
Immunoreactivity of tissue amyloid for [kappa] or [lambda] light chain is evidence for AL amyloidosis.
18F]Flutemetamol is a GE Healthcare PET imaging agent in development for the detection of beta amyloid deposits in the brain.
Participants who tested positive for amyloid on florbetapir (Amyvid) PET scan at baseline were five times more likely to convert to Alzheimer's dementia within 3 years than were amyloid-negative subjects, data from the large, multisite imaging registry showed.
The findings by Stony Brook University researchers suggested that targeting early buildup of amyloid in brain blood vessels could be a potential treatment strategy in early stage disease.
Smith was one of a tiny handful of researchers who weren't jumping on the amyloid bandwagon.