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anaplasia

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.03 sec.
anaplasia [‚an·ə′plāzh·ə]
(medicine)
Reversion of cells to an embryonic, immature, or undifferentiated state; degree usually corresponds to malignancy of a tumor.


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(3) The tumor we describe belongs in this category, although our case is unique in view of our distinguishing findings of the absence of fibrosis and neuronal tissue and the presence of abundant gemistocytes, mild vascular proliferation, perivascular cuffing, mild cellular anaplasia, and mitoses.
Fibromatosis occupies an intermediary position, and microscopic sections contain markedly cellular lesions of mature proliferative fibroblastic tissue, with infrequent mitoses and occasional atypia, but no frank anaplasia.
Nuclear anaplasia can be seen, but mitotic figures are rare.
 
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