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anaplasia

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
anaplasia [‚an·ə′plāzh·ə]
(medicine)
Reversion of cells to an embryonic, immature, or undifferentiated state; degree usually corresponds to malignancy of a tumor.
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1) The term "dedifferentiated" implies that a portion of cells from the chondrosarcoma have degenerated into a high-grade malignant form that is characterized by pleomorphism, anaplasia, hypercellularity, and increased mitoses.
Radiological case of the month: Charles E. Lohr III, MD; Bahair H. ... by Lohr, Charles E. III; Ghazi, Bahair H.; Schwab, Mark H.; Krantz, William A. Jr.; Nuss, Michelle A. / Applied Radiology
Based on their cellularity and degree of anaplasia, chondrosarcomas are classified as either low-, medium-, or high-grade tumors.
Chondrosarcoma of the larynx by Thompson, Lester D.R. / Ear, Nose and Throat Journal
Nuclear anaplasia can be seen, but mitotic figures are rare.
Carotid body tumor (paraganglioma) by Pantanowitz, Liron / Ear, Nose and Throat Journal
 
 
 
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