androgen


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Related to androgen: estrogen, testosterone, Androgen deficiency

androgen

(ăn`drəjən): see testosteronetestosterone
, principal androgen, or male sex hormone. One of the group of compounds known as anabolic steroids, testosterone is secreted by the testes (see testis) but is also synthesized in small quantities in the ovaries, cortices of the adrenal glands, and placenta, usually
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.

Androgen

One of a class of steroid hormones. Androgens play a major role in the development and maintenance of masculine secondary sexual characters, for example, the seminal vesicle and prostate gland of the male mammal, and the comb, wattles, and spur of the male fowl. They also influence certain other secondary sexual characters, such as hair growth pattern and voice quality in humans. In the fowl, they affect the pattern and seasonal coloration of its feathers, as well as crowing. In addition, androgens affect nitrogen metabolism (anabolic). Androgens are produced in the testis, ovary, adrenal, and most likely, in the placenta. A small portion of the androgen is from corticoids, or adrenal cortex steroids, and from other C21 steroids, such as progesterone. See Hormone, Ovary, Progesterone, Steroid, Testis

androgen

[′an·drə·jən]
(biochemistry)
A class of steroid hormones produced in the testis and adrenal cortex which act to regulate masculine secondary sexual characteristics.
References in periodicals archive ?
Professor Gail Risbridger said: "The results indicate that these persistent cancer cells somehow differ from cancer cells that respond to androgen withdrawal, and are likely to be the precursor cells that lead to advanced androgen-resistant disease.
Disproportionate stimulation of LH in - relation to follicle stimulating hormone (FSH) may lead to a thickening of the ovarian stroma and cause a consequent increase in androgen production from the ovary directly.
Nor were there differences in biochemical failure, regional or distant recurrence, pelvic metastases, or the need for a second course of androgen blockade.
A normal prostate requires basal concentrations of androgen for growth and survival.
Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors.
Thus, experimental data and clinical results concur in indicating a correlation between fusion gene expression and the role of the androgen pathway.
Androgens have been described as any chemical with testosterone-like action.
KEY WORDS: androgen-independent, androgen receptor, arsenic, cancer progression, hormone refractory, malignant transformation, MAP kinase, prostate, Ras.
Azziz (Center for Androgen Related Disorders, Cedars-Sinai Medical Center) presents the latest findings on the etiology, pathophysiology, clinical manifestations, genetics, and consequences of androgen excess disorders in women.
The lemur moms' androgen concentrations were higher overall when they were carrying male fetuses.
Scientists in the Catterall lab are studying the effects of androgen in the kidney, rather than in the reproductive system.
The Food and Drug Administration has begun a formal process to evaluate the efficacy of two estrogen / androgen combinations currently marketed for the treatment of moderate to severe menopausal hot flashes in women who don't respond to estrogen alone.