It can be speculated that low concentrations of APE cause immunostimulatory LPS effects, while at higher concentrations inhibitory effects of andrographolide and other Andrographis paniculata
secondary metabolites are dominant.
The objective of this study was to evaluate the effects of Andrographis paniculata
on growth performance and carcass characteristics in goats.
Mosquitocidal effect of Andrographis paniculata
Nees against the malaria vector, Anopheles stephensi Liston (Diptera: Culicidae).
In one double-blind, randomized, placebo-controlled trial (entitled, "Efficacy of an Andrographis paniculata
composition (Paractin[R]) for the relief of rheumatoid arthritis symptoms: A prospective randomized placebo-controlled trial," the researchers looked at the effects of Paractin[R] on 60 patients with chronic active rheumatoid arthritis.
In an immunity test conducted by Henan University in China, scientists rated andrographis paniculata
as the most potent anti-viral herbal medicine ever discovered.
Hepatic disorder like liver cirrhosis and others like jaundice are treated by the folk medical practitioners in this region using leaf extracts of Andrographis paniculata
, Allium sativa, Hydrastis canadensis and Artemesia annua)
Andrographolides from the Asian herb Andrographis paniculata
and curcuminoids from turmeric have multi-targeted, complementary actions that powerfully counter the inflammatory response.
Silymarin from Silybum marianum, andrographolide form Andrographis paniculata
, curcumin form Curcuma longa, picroside and kutkoside form Picrorrhiza kurroa, phyllanthin and hypophyllanthin from Phyllanthus niruri, glycyrrhizin from Glycyrrhiza glabra are traditionally used in the treatment of liver diseases and represent the phytochemical constituents and have been studied for their chemical and biological profile and clinical efficacy (24).
Among the herbs that Mahady and her co-investigators found promising was Andrographis paniculata
, a plant long used in traditional Chinese and Indian medicine for treating the common cold, flu and other infections.
For example, Andrographis paniculata
, which has been used for liver disorders in Ayurveda, offers a solution for skin aging via its anti-inflammatory active agent, andrographolide.
has been used in Nordic countries to provide relief from, and to reduce the duration of, symptoms of the common cold and flu.