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androstane |
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androstane [′an·drə‚stān] (biochemistry) C19H32The parent steroid hydrocarbon for all androgen hormones. Also known as etioallocholane. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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These UGT isoforms are induced by
aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR),
and pregnane-X receptor (PXR) agonists. The environmental pollutant 1,1-dichloro-2,2-bis
(p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A
expression through the constitutive androstane receptor and pregnane X
receptor. Pregnane X receptor (PXR), constitutive androstane receptor
(CAR), and benzoate X receptor (BXR) define three pharmacologically
distinct classes of nuclear receptors. |
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