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androstane

   Also found in: Medical, Wikipedia, Hutchinson 0.03 sec.
androstane [′an·drə‚stān]
(biochemistry)
C19H32The parent steroid hydrocarbon for all androgen hormones. Also known as etioallocholane.


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These UGT isoforms are induced by aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR), and pregnane-X receptor (PXR) agonists.
The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.
 
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