androsterone


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androsterone

[‚an′dräs·tə‚rōn]
(biochemistry)
C19H30O2 An androgenic hormone occurring as a hydroxy ketone in the urine of men and women.
References in periodicals archive ?
The classic AAS is testosterone, which is metabolized into the active metabolites of dihydrotestosterone, androstanolone, estradiol, androsterone, and androstenedione.
Androsterone can be derived not only from AD4 and dihydrotestosterone in the conventional pathway but also from 5[alpha]-pregnane-3[alpha],17[alpha]-diol-20-one in the backdoor pathway (12, 13).
The remaining steroids tested, epitestosterone, dihydrotestosterone, dehydroepiandrosterone, androsterone, 19-hydroxytestosterone, ethisterone, and cyproterone acetate, showed no significant peaks above background noise.
13]C VALUES FOR ACETYLATED ANDROSTERONE AND ETIOCHOLANOLONE FROM ATHLETES' URINES WITH HIGH EPITESTOSTERONE CONCENTRATIONS
The urinary androsterone and etiocholanolone [[delta].
Testosterone, testosterone glucuronide (TG), androsterone, androsterone glucuronide (AG), etiocholanolone, etiocholanolone glucuronide (EtG), 17[alpha]-hydroxyprogesterone (17[alpha]OHP), and Escherichia coli [beta]-glucuronidase were purchased from Sigma.
Endogenous steroids (testosterone, androsterone, and etiocholanolone) were quantified using the responses of the target compounds relative to the internal standards, calculated from an extracted sample of distilled water containing 1.
This possibility is supported by reports that treatment with T3 in some patients caused an increase of androsterone production (27-29).
Androsterone, etiocholanolone, 11[beta]-hydroxyandrosterone, 11[beta]-hydroxyetiocholanolone, androst-5-en-3,17-diol, 5a-androstan-3a,17[beta]-diol, 5[beta]-androstan-3a,17[beta]-diol, dihydrotestosterone, DHEA, T, and E were purchased from either Sigma Chemical Co.
Urinary androsterone and etiocholanolone account for ~70% of a dose of T [17]; however, many other endogenous steroids are metabolized to androsterone and etiocholanolone, and neither their concentrations nor their ratio is a useful marker of T administration.
An example matrix ion is the endogenous steroid androsterone (m/z 434 for the di-TMS derivative), which is present in urine at concentrations 100-fold greater than some of the anabolic steroids screened for.