aneuploidy


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Related to aneuploidy: aneuploidy screening, Turner syndrome

aneuploidy

[′a·nyü‚plȯid·ē]
(genetics)
Deviation from a normal haploid, diploid, or polyploid chromosome complement by the presence in excess of, or in defect of, one or more individual chromosomes.
References in periodicals archive ?
The new work, she notes, "shows that there are things in the environment that can affect aneuploidy.
The CGH screening of 219 placental tissues from a population of live-born infants yielded 25 specimens that were suspected of having mosaic aneuploidy due to the presence of a discernible shift in the ratio profile from 1:1.
But the positive predictive value is lower in the general population because of the lower prevalence of aneuploidy.
Non-invasive prenatal testing of fetal whole chromosome aneuploidy by massively parallel sequencing.
Biochemical marker-based and ultrasound-based non-invasive fetal aneuploidy screening tests, although safe, have poor accuracy with high false-positive and false-negative rates.
Sperm aneuploidy was measured as the frequency per 10,000 sperm.
Another option for screening for aneuploidy that is gaining popularity is combining first- and second-trimester screening.
Development and validation of concurrent preimplantation genetic diagnosis for single gene disorders and comprehensive chromosome aneuploidy screening without whole genome amplification.
And despite a 2012 committee opinion from the American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine endorsing the testing only in women at higher risk for aneuploidy, many obstetricians began offering the testing regardless of risk status, he added.
9] This technique also enabled us to provide rapid results with conclusive outcomes within 24 hours of receipt of the sample, [5,9,11,12] which is about half the time of fast FISH aneuploidy screening, because it is possible to interpret the profiles of several samples in few minutes.
All carcinogens cause aneuploidy, even though they may not cause genes to mutate.