angioedema


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Related to angioedema: Hereditary angioedema

angioedema

[‚an·jē·ō·i′dē·mə]
(medicine)
The development of giant hives beneath the surface of the skin, especially around the eyes and lips; usually due to an allergic response.
References in periodicals archive ?
Immunologists should also be aware that the angioedema may be a result of rheumatoid arthritis and can herald a flare.
CSL Behring therapies are indicated for the treatment of coagulation disorders including hemophilia and von Willebrand disease, primary immune deficiencies, hereditary angioedema and inherited respiratory disease.
Hereditary angioedema (HAE) is a rare acute inflammatory condition characterized by episodes of severe, often painful swelling affecting the extremities, gastrointestinal tract, genitalia, and larynx.
In cases of severe angioedema, your doctor may show you how to self-inject adrenaline.
The patient complied and, through May 2012, had experienced no more angioedema after drinking coffee.
Type 1 hereditary angioedema results from a mutation in C1 esterase inhibitor gene leading to decreased secretion of the protein, thus leading to reduced plasma levels.
For urticaria and angioedema, a positive response required resolution of all urticaria and angioedema (historical dermographism was required to return to baseline).
Pathophysiologically, angioedema is caused by postcapillary venule leakage and edema formation in subcutaneous or mucosal soft tissues.
Hereditary Cl-esterase inhibitor deficiency is accompanied by two dermal manifestations, angioedema and erythema marginatum.
Chronic urticaria with angioedema presents a challenge in its treatment in that it Often requires long-term follow-up," said Dr.
HAE is an especially challenging disease for patients to manage, said Anthony Castaldo, President of the Hereditary Angioedema Association (US HAEA), a non-profit patient services and research organization with a membership of over 5,000 HAE patients in the United States.