angiogenesis

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Related to angiogenic: angiogenic growth factors

angiogenesis

[¦an·jē·ō¦jen·ə·səs]
(embryology)
The origin and development of blood vessels.
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Circulating angiogenic factors and the risk of preeclampsia.
If angiogenic biomarker levels remain normal, we can reassure patients that fewer than 5 out of 100 will not develop serious complications, such as preeclampsia, severe growth restriction or fetal death," said Jane E.
But its association with angiogenic factors is unclear.
Siphonaxanthin also inhibited microvessel formation in rat aortic ring angiogenic model.
Repair is assembling a portfolio of technologies for the sustained release delivery of angiogenic factors locally at the site of tissue injury, to induce a lasting, angiogenic response that yields stable collateral blood vessels.
The Company is also conducting an aggressive preclinical plan for squalamine in the treatment of angiogenic eye diseases.
The successful construction of dual recombinant angiogenic growth factor genes further demonstrates Collateral's technical leadership and ingenuity in the cardiovascular gene therapy arena," said Christopher J.
There are four steps involved in the growth of blood vessels within tumors: i) the release of angiogenic growth factors by cancerous cells, ii) the disintegration of the basement membrane of a pre-existing capillary through the action of MMPs, iii) the proliferation and migration of endothelial cells to form sprouts, and iv) the formation of a capillary tube through the eventual contact of sprouts (Li et al.
Angiopoietin-2 promotes angiogenic changes when VEGF is present.
We believe that our approach to treating angina by infusing angiogenic adenovectors to trigger the growth of new blood vessels in the heart represents a best-in-class technique -- and while we appreciate and respect other companies' interests in attempting to secure competing patent claims, we intend to continue to defend and to strengthen our IP portfolio for delivering angiogenic DNA sequences to the heart.
Investigational angiogenic gene therapy product, Ad5FGF-4
The study showed positive outcomes of its therapeutic angiogenic product Ad5FGF-4 in the treatment of patients with chronic stable angina.