ankyrin


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ankyrin

[aŋ′kī·rən]
(cell and molecular biology)
A protein found in the cell membrane of erythrocytes that attaches the membrane to the cytoskeleton protein spectrin.
References in periodicals archive ?
Also, in a recent association study, COGA researchers have found that alcoholism association with the DRD2 region actually may be the result of an association with the nearby ankyrin repeat and kinase domain containing 1 (ANKKI) gene (Dick et al.
The center has discovered that B cell scaffold protein with ankyrin repeats (BANK), a kind of adapter molecule, inhibits the immune response of the B cell.
This gene encodes a 153-160 kDa protein with at least 11 N-terminal ankyrin repeats and a C-terminus with several tandem repeats but no homology with other proteins.
receptors, kinases and angiogenesis pathways) - Monoclonal antibodies, mAb fragments, DARPins (designed ankyrin repeat proteins) and visual cycle modulators.
In a one-year re-integration phase I will perform follow-up mechanistic structural studies in the Olga Mayans lab (University of Liverpool) to determine the structural basis how the CARP (cardiac ankyrin repeat protein)-titin signaling axis mediates cardiomyocyte protection, and in the Labeit lab (University of Heidelberg, Medical Faculty Mannheim) how to perturb activity of this complex by small molecules.
Parthenolide may interact with the transient receptor potential ankyrin 1 (TRPA1) desensitizing the channel (Materazzi et al.
receptors, kinases and angiogenesis pathways) -- Monoclonal antibodies, mAb fragments, DARPins (designed ankyrin repeat proteins) and visual cycle modulators.
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
The presence of 6 conserved ankyrin repeats in SgI[kappa]B and its close phylogenetic relationship with other I[kappa]Bs strongly suggest that SgI[kappa]B belongs to the I[kappa]B superfamily.
Source:RefSeq mRNA;Acc :NM_001109946] ENSSSCG00000005 607 RALGPS 1 Ral GEF with PH domain and SH3 binding motif 1 [Source:HGNC Symbol;Acc:16851] ENSSSCG00000005 679 ASB6 Sus scrofa ankyrin repeat and SOCS box containing 6 (ASB6), mRNA.
Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors," Journal of Virology 87(10): 5868-5881.
Apart from this falcipain-II enzyme also degrades the erythrocyte-membrane skeletal proteins which include ankyrin and the band 4.