anterior horn cell


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anterior horn cell

[an¦tir·ē·ər ′hȯrn ‚sel]
(neuroscience)
A motor neuron in the anterior horn gray matter of the spinal cord; directly innervates skeletal muscle.
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References in periodicals archive ?
Clinical and electrodiagnostic data suggested the involvement of spinal anterior horn cells, resulting in a poliomyelitis-like syndrome.
Nonspecific immunoglobulin and plasmapheresis should be considered for patients with Guillain-Barre syndrome but are not indicated for patients with paralysis due to damage of anterior horn cells (30).
In the cases of WNV-associated AFP, clinical, laboratory, and electrophysiologic findings suggested pathology localized to anterior horn cells and motor axons, similar to that seen in acute poliomyelitis.
The poliovirus infects the spinal cord anterior horn cells and other motor neuron cells.
Destruction of the spinal anterior horn cells may also cause acute flaccid paralysis (AFP), presenting as asymmetric limb weakness, hypoflexia or areflexia, and acute bowel or bladder dysfunction that may appear without signs of meningoencephalitis.
Werdnig-Hoffman disease is a neuromuscular disorder caused by loss of anterior horn cells and motor nuclei of cranial nerves V through VIII.

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