androgen

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androgen

(ăn`drəjən): see testosteronetestosterone
, principal androgen, or male sex hormone. One of the group of compounds known as anabolic steroids, testosterone is secreted by the testes (see testis) but is also synthesized in small quantities in the ovaries, cortices of the adrenal glands, and placenta, usually
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.

Androgen

One of a class of steroid hormones. Androgens play a major role in the development and maintenance of masculine secondary sexual characters, for example, the seminal vesicle and prostate gland of the male mammal, and the comb, wattles, and spur of the male fowl. They also influence certain other secondary sexual characters, such as hair growth pattern and voice quality in humans. In the fowl, they affect the pattern and seasonal coloration of its feathers, as well as crowing. In addition, androgens affect nitrogen metabolism (anabolic). Androgens are produced in the testis, ovary, adrenal, and most likely, in the placenta. A small portion of the androgen is from corticoids, or adrenal cortex steroids, and from other C21 steroids, such as progesterone. See Hormone, Ovary, Progesterone, Steroid, Testis

androgen

[′an·drə·jən]
(biochemistry)
A class of steroid hormones produced in the testis and adrenal cortex which act to regulate masculine secondary sexual characteristics.
References in periodicals archive ?
While the antiandrogens could be used in more severe cases, there are a variety of other medications and combinations of medications which could be used to control less severe cases.
Sexuality changes in prostate cancer patients receiving antihormonal therapy combining the antiandrogen flutamide with medical (LHRH agonist) or surgical castration.
Nonsteroidal antiandrogens and luteinizing hormone-releasing hormone (LHRH) analogues are mostly used for metastatic prostate cancer.
If the cancer is detected early, androgen ablation can be used for therapy either via chemical castration by use of antiandrogens, or surgical removal of the testicles, the major producers of androgens.
Specific to prostate cancer, antiandrogen treatment may be instituted.
Medroxyprogesterone acetate is not an antiandrogen per se but is, rather, a progestational agent that reduces testosterone levels indirectly Leuprolide acetate, an LHRH agonist, has a comparable effect and has been effective in patients who did not respond to medroxyprogesterone acetate and other agents.
The new treatment is a member of the antiandrogen family of drugs, called Casodex, which has been developed by AstraZeneca.
Last year, Guillette brought up this antiandrogen hypothesis during a presentation of his work at a meeting in Atlanta; among the attendees was L.
Klotz L): Degarelix monotherapy versus luteinizing hormone-releasing hormone (LHRH) agonists plus antiandrogen flare protection in the treatment of men with advanced prostate cancer.
KEY WORDS: antiandrogen, AR-antagonism, concentration addition, endocrine disruption, fungicide, mixture, pesticide.
The one exception was with the weakest antiandrogen, linuron, in a laboratory with reduced sensitivity because of high coefficients of variation in all tissue weights.