androgen

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androgen

(ăn`drəjən): see testosteronetestosterone
, principal androgen, or male sex hormone. One of the group of compounds known as anabolic steroids, testosterone is secreted by the testes (see testis) but is also synthesized in small quantities in the ovaries, cortices of the adrenal glands, and placenta, usually
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.

Androgen

One of a class of steroid hormones. Androgens play a major role in the development and maintenance of masculine secondary sexual characters, for example, the seminal vesicle and prostate gland of the male mammal, and the comb, wattles, and spur of the male fowl. They also influence certain other secondary sexual characters, such as hair growth pattern and voice quality in humans. In the fowl, they affect the pattern and seasonal coloration of its feathers, as well as crowing. In addition, androgens affect nitrogen metabolism (anabolic). Androgens are produced in the testis, ovary, adrenal, and most likely, in the placenta. A small portion of the androgen is from corticoids, or adrenal cortex steroids, and from other C21 steroids, such as progesterone. See Hormone, Ovary, Progesterone, Steroid, Testis

androgen

[′an·drə·jən]
(biochemistry)
A class of steroid hormones produced in the testis and adrenal cortex which act to regulate masculine secondary sexual characteristics.
References in periodicals archive ?
Clinical review: antiandrogens for the treatment of hirsutism: a systematic review and meta-analysis of randomized controlled Wals.
Development of a second-generation antiandrogen for treatment of advanced prostate cancer.
OCPs, antiandrogens, metformin, eflomithine, and mechanical hair removal are recommended for hirsutism.
Similarly reduction of testicular weight and associated histological changes were noted after administration of antiandrogen in an androgen stimulated testes of rats in a study conducted by Wason et al18.
If the cancer is detected early, androgen ablation can be used for therapy either via chemical castration by use of antiandrogens, or surgical removal of the testicles, the major producers of androgens.
49) The pharmacological model's shortcoming lies in that it only controls a sex offender's behavior so long as the offender continues to receive some form of hormone-blocking antiandrogen treatment.
In this investigation, flutamide will be injected to male mice to be able to determine the changes taking place in the presence of this antiandrogen in the concentrations of zinc in prostate, fructose in seminal vesicle and in the development of spermatogenesis in mice.
Aldactone acts as an antiandrogen and actually decreases the amount of free, circulating testosterone, thus impacting most significantly on hirsutism (Richardson, 2003).
By taking premarin (an estrogen) and spirolactone (an antiandrogen or anti-male hormone), Boylan transforms himself into herself.
21) It relies heavily on the use of SSRIs (Selective Serotonin Reuptake Inhibitors) in mild cases and on antiandrogen treatment in extreme cases.
The treatment is a new member of the antiandrogen family of drugs, called Casodex, which has been developed by AstraZeneca.