Co-infection is associated with higher rates of HBV persistence after acute infection, and among individuals with CHB, higher HBV DNA levels, a higher prevalence of HBV e antigenaemia
, and an increased risk of progression to fibrosis, cirrhosis and possibly hepatocellular carcinoma (HCC).
3] In two ART cohorts in SA, the prevalence of newly-diagnosed antigenaemia
among patients with a [CD4.
and viraemia: A common event?
Asadullah K, Prosch S, Audring H et al: A high prevalence of cytomegalovirus antigenaemia
in patients with moderate to severe chronic plaque psoriasis: an association with systemic tumour necrosis factor alpha overexpression.
was low and continued to decrease significantly in the age group 15-25 years in villages receiving MDA+VC in contrast to villages receiving only MA.
However, there was no significant difference in antigenaemia
levels between pre-treatment (day 0) and PT samples collected on day 7 onwards till day 365.
Plasma cytomegalovirus DNA, pp65 antigenaemia
and a low CD4 cell count remain risk factors for cytomegalovirus disease in patients receiving highly active antiretroviral therapy.
All the biopsies that showed MCGN had IgM and C3 deposits, supporting chronic antigenaemia
as a possible cause.
Seroconversion can occur as late as 6 months after exposure, while detectable levels of viraemia and p24 antigenaemia
develop over the first 3--4 weeks of infection.
The pp65 antigenaemia
test, a well established diagnostic technique for HCMV, was also carried out on the patients.
16] Some studies have shown no differences between HIV-positive and HIV-negative patients, while others have shown that vascular access-related infections were more prevalent in those with lower CD4 counts, hepatitis B antigenaemia
and injecting drug use.
Methods: The PCR based RFLP and the multiplex nested PCR were applied on standard strain of HCMV AD169, 4 clinical HCMV isolates and 70 clinical specimens positive for HCMV by pp65 antigenaemia
assay or nested PCR for mtr II region or both.