antihypertensive agent


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antihypertensive agent

[‚an·tē‚hī·pər′ten·siv ′ā·jənt]
(pharmacology)
A substance, such as reserpine, that reduces hypertension.
References in periodicals archive ?
d) Discontinue nonpharmacological management and start combination pharmacological management using two antihypertensive agents
8,9) It is also evident based on clinical trial results that most persons with hypertension require therapy with a combination of 2 or more antihypertensive agents to achieve currently recommended BP targets.
Selection of an optimum antihypertensive agent is based on the patient's clinical status, age, volume status, coexisting medical conditions, presenting complications, end-organ compromise and pharmacodynamic effects of the drug.
Approximately 76% of all the 75 million hypertensives require two or more antihypertensive agents, and people are sick of taking pills.
AR9281 inhibits s-EH, an enzyme that plays a key role in the cytochrome P450 pathway of arachidonic acid metabolism, and offers a unique mechanism of action as an antihypertensive agent," said Dinesh V.
We believe this candidate has considerable potential as an improved antihypertensive agent, based on its nitric oxide-donating properties," said Jacques Djian MD.
The dose of antihypertensive agent was adjusted as necessary to achieve the desired BP response over a 24-hour period.
Beginning just before patients went into cardiac surgery, investigators monitored each patient's blood pressure (BP) and administered the assigned antihypertensive agent, at their discretion, if it became too high.
Some of the drugs that are commonly administered by injectable drug delivery include analgesics, antibiotics, immunosuppressive agents, antihypertensive agents, vasodilators, chemotherapeutic agents and antiarrhythmic drugs.
This is the first study to consider sex as an element in the selection of antihypertensive agents or base the choice of a specific drug on the various factors accounting for the elevation in blood pressure," lead author of the study, Carlos Ferrario, said.
When it comes to preventing atrial fibrillation (AF), not all antihypertensive agents are created equal.