antifibrinolysin

(redirected from antiplasmin)
Also found in: Medical.

antifibrinolysin

[¦an·tē‚fī·brə′näl·ə·sən]
(biochemistry)
Any substance that inhibits the proteolytic action of fibrinolysin.
References in periodicals archive ?
2]- antiplasmin vWD N N/[up arrow] Inherited platelet N N defects Bleeding Inherited bleeding time/ condition TT PFA [down arrow] Fibrinogen [up arrow] N/[up arrow] * Dysfibrinogenaemia [up arrow] N (bleeding disorder) [down arrow] Prothrombin N N [down arrow] Factor V N N [down arrow] Factor VII N N [down arrow] Factor VIII N N [down arrow] Factor IX N N [down arrow] Factor X N N [down arrow] Factor XI N N [down arrow] Factor XIII N N [down arrow] N N [[alpha].
24) A study on black-headed vultures (Coragyps atratus) indicated that coagulation and fibrinolysis is activated simultaneously in that species, as in other vertebrates, (9) whereas an early study of Japanese quail (Coturnix japonica) reported that spontaneous but delayed fibrinolysis takes place (25) and suggested that the activity of avian antiplasmin is equal to that of human antiplasmin.
Plasminogen, AT3, protein C and S, alpha-2 antiplasmin and alpha-1 antitrypsin are also produced in the liver.
3%) patients include local causes, heterozygosity of inherited coagulation factor deficiency, vWD, some forms of dysfibrinogenemias, platelet function defects like release reaction abnormalities, hereditary haemorrhagic telangiectasia, allergic and other vascular purpuras, a2 antiplasmin deficiency, elevated levels of plasminogen activator, testing at inappropriate post transfusion time, high levels of one factor masking deficiency of the other and result fluctuation from time to time.
MMP-12 has a broad range of substrates, including α-1 proteinase inhibitor, α-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.
ECE protects the cardiovascular system via promotion of fibrinolysis through antiplasmin inhibition and ACE inhibition.
Measurements included complete blood count (CBC); platelets; PT; activated partial thromboplastin time (APTT); fibrinogen (clottable, immunological); coagulation factors II, V, VII, VIII, IX, X, XI, XII; anti-thrombin (AT); alpha-2 antiplasmin (AP); Protein C (PC); mixing studies; lupus anticoagulant screening; plasminogen; thrombin-anti-thrombin; fibrin degradation products (FDP); d-dimer; and thrombin time.
Inhibitory proteins, such as plasminogen activator inhibitor-1 (PAI-1) and antiplasmin, help regulate the rate of fibrinolysis (Diethorn & Weld, 1989; Comp, 1990).
The methods used were as follows: fibrinogen was measured by the Clauss method [4] protein S activity was measured using the IL Test[TM], an assay based on the prolongation of prothrombin time; protein C activity, tissue plasminogen activator (tPA), antithrombin III (AT III), plasminogen activator inhibitor (PAI) and antiplasmin were measured photometrically using chromogenic techniques (Chromogenix[TM] kits).
Innovative Alpha-2 Antiplasmin Diagnostic Testing Technologies and Emerging Markets
Uromodulin, SERPINF1 (serpin peptidase inhibitor, clade F, [alpha]-2 antiplasmin, pigment epithelium derived factor, member 1), and CD44 were verified in an independent cohort and shown to differentiate patients with AR from other groups.
Coagulation factors II, V, IX, X, XI, and XII, plasminogen, and alpha-2 antiplasmin and risk of coronary heart disease.