antitussive


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antitussive

[¦an·tē¦təs·iv]
(pharmacology)
An agent, such as benylin expectorants, that relieves coughing.
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Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae Cirrhosae.
Previous studies showed a potent relaxant effect of the extract and safranal on tracheal chains, its stimulatory effect on B2-adrnoceptors, inhibitory effect on histamine (Hi) receptors, antitussive effect on guinea pigs and its effect on Th1/1h2 balance (Boskabady and Aslani 2006; Boskabady etal.
A recent randomized, placebo-controlled trial has shown that codeine, a common antitussive agent, was not effective in the management of cough in COPD patients (Smith et al.
Food and Drug Administration (FDA) has taken action to remove more than 200 hydrocodone antitussive products from the market due to concerns about medication errors.
Central acting antitussive agents are selected as the general treatment in prolonged cough, but there are many patients who do not respond to the treatment and in the clinical practice guidelines by American College of Chest Physicians (ACCP), it is stated that codeine phosphate and dextromethorphan hydrobromide which are central acting antitussive agents are not recommended (Irwin et al.
We continued to advance the development of our product candidates and submitted a regulatory filing with the FDA for an extended-release antitussive product (CRTX 067) that, if approved, would compete directly in the large prescription antitussive market.
According to data derived from Source Pharmaceutical Audit Suite, January-December 2008, Wolters Kluwer Health, in 2008, there were over 30 million prescriptions and nearly $1 billion dollars in sales generated for oral antitussives; however, most oral antitussive products that are currently marketed are in an immediate-release formulation (over 25 million prescriptions annually) requiring dosing every four to six hours, which can be inconvenient and adversely affect patient compliance.
These TCMs are Yi Mu Cao Gao (a motherwort herb electuary sticky syrup), Gan Mao Zhi Ke Ke Li (an antipyretic and antitussive granule), and Kang Gu Sui Yan Pian (an osteomyelitis treatment tablet).
Its trunk bark and seeds are traditionally used as an antispasmodic, anti-inflammatory, antitussive, and mainly for the treatment of asthma (Correa 1984).
In 1998, Harish Joshi, PhD, professor of cell biology at Emory University School of Medicine, and his colleagues discovered that noscapine, an opium alkaloid that has been used as an antitussive agent in Japan, Sweden and South Africa, has potent antitumor activity against solid murine lymphoid tumors and against human breast and bladder tumors implanted in nude mice.
The antitussive effect of this plant on the guinea pig (Boskabady et al.
Codeisan(R) is prescribed for moderate pain and is a useful antitussive for treating discomforts associated with severe cough.