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apomorphine

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.03 sec.
apomorphine [¦ap·ə¦mȯr‚fēn]
(pharmacology)
C17H17NO2A crystalline alkaloid obtained by dehydration of morphine; acts as a powerful emetic.


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Tokyo, Japan, Feb 23, 2006 - (JCN) - Kyowa Hakko Kogyo announced on February 22 that it has concluded a licensing agreement with UK company Britannia Pharmaceuticals for a self-injectable formulation of apomorphine.
Patients were randomized to commence either sildenafil or apomorphine treatment.
These investigators administered two proteasomal inhibitors (epoxomicin and PSI) to rats over a 14-day period and then observed a progressive deterioration in motor function over a 2-week period, which improved after administration of the dopamine agonist apomorphine.
 
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