Before 2008, Lassa virus was the only arenavirus
known to cause HF in Africa.
A new arenavirus
in a cluster of fatal transplant-associated diseases.
Members of the virus genera Hantavirus (family Bunyaviridae) and Arenavirus
(family Arenaviridae) are rodent-borne viruses with cosmopolitan distributions, primarily associated with the rodent families Cricetidae (New World) and Muridae (Old World).
Human infection with an arenavirus
is likely to be very uncommon.
typically is associated with wild wood rats and believed to be transmitted to humans in dust carrying an infected rodent's urine, feces or saliva, a health expert said Friday.
Because of lack of data about arenavirus
occurrence and effects in southwestern Africa, we conducted a study of small mammals from Namibia to detect infection with arenaviruses
I will use biochemistry, microscopy, and cell biological assays to examine in detail the virus-host interplay with these factors and will identify promising new antiviral targets for arenavirus
family members that cause human disease.
Intensive laboratory investigation attributed the outbreak to a novel arenavirus
, dubbed 'Lujo' (i.
They discuss such aspects as viral bioterrorism and antiviral countermeasures, antiviral drug targets and strategies, perspectives on the therapy against Arenavirus
infections, Ebola, exploiting the error-prone replication of riboviruses for antiviral therapy, the structural biology of flaviviral replication and opportunities for drug design, West Nile virus, the emergence of pandemic influenza A, smallpox, and the role of the Vaccina virus E3L and K3L genes in viral countermeasures to the host interferon response.
From March 2001 to January 2003, woodrat middens were excavated and occupants captured as part of an ongoing study examining the ecology of the White Water Arroyo arenavirus
The presence of IgG against WWAV in acute-phase serum samples (all collected within 10 days of illness onset) implied past infection with WWAV or an arenavirus
antigenically closely related to WWAV.
All South African-based medical emergency air services met with the national health department's Communicable Diseases Directorate in Gauteng on 15 September to 'tighten up communications' after the unprecedented fatal arenavirus