Second, the lack of some clinicopathological parameters of the study cohort such as accurate information on aristolochic acid
medication history, surgical margin status, and lymphovascular invasion status which may reduce the strength of this study.
They used several search engines to include all publications that are about or refer to aristolochic acid
and Chinese herbal nephropathy and identified 42 different case studies and one trial relating to the management of the disease.
It is hoped the work will identify exactly how aristolochic acid
causes cells to become cancerous.
For example, she said, aristolochic acid
is not produced in the United States and the federal government has an import ban on it, so if the law were being enforced it would not be available for sale here.
Dirty Dozen: 12 Supplements to Avoid Name(s) Dangers Regulatory Actions DEFINITELY HAZARDOUS: Documented organ failure or known carcinogenic properties Aristolochic acid
Potent human carcinogen; FDA warning to (Aristolochia, kidney failure, sometimes consumers and industry birthwort, requiring transplant; deaths and import alert in snakeroot, reported.
All three have been used as weight-loss aids, while aristolochic acid
has also been used to alleviate gastrointestinal and other health problems.
They will first develop testing methods for supplements containing ephedrine-type alkaloids and aristolochic acid
On May 31, 2000, the Food and Drug Administration issued a letter to health care professionals concerning the nephrotoxicity and carcinogenicity of botanical products containing aristolochic acid
A mixture of Chinese herbs, including aristolochic acid
, a nephrotoxic substance, has been used primarily by women for weight loss resulting in a unique type of chronic interstitial fibrosis of the kidney and tubular atrophy.
and its salts, as well as Aristolochia spp and their preparations (substances that act as powerful carcinogens).
nephropathy resulting from its use as an additive in weight-loss drugs was first reported in Belgium.
The plants of the genera Aristolochia and Asarum became the interesting topic for the phytochemical and pharmaceutical researchers since the discovery of aristolochic acid