Louis have found a way to relieve the joint and muscle pain that often accompanies aromatase inhibitors
, allowing women to continue taking these medications.
The ZO-FAST trial: zoledronic acid effectively inhibits aromatase inhibitor
associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: 24 month BMD results.
The aromatase inhibitors
anastrozole, exemestane and letrozole, within their licensed indications, are recommended as options for the adjuvant treatment of early oestrogen-receptor-positive invasive breast cancer in postmenopausal women.
Thousands of women have already beat breast cancer thanks to recent research on aromatase inhibitors
," says Dr.
The results of this study involving 10 men diagnosed with IHH associated with PB indicate that treatment with the aromatase inhibitor
anastrazole returned LH and testosterone levels to the normal range and also lowered estradiol levels.
Entinostat's proven ability to target multiple mechanisms of resistance establishes it as a promising candidate for preventing and overcoming aromatase inhibitor
resistance through epigenetic modulation.
But aromatase inhibitors
are not an option in premenopausal patients because they're ineffective in that setting.
In a study of 252 postmenopausal women with breast cancer under treatment with an aromatase inhibitor
, bone mineral density at the lumbar spine was significantly higher among those treated with denosumab compared with those on placebo after 12 months of treatment, according to the statement.
This interesting review article discusses the well-known clinical finding that some patients with breast cancers resistant to one aromatase inhibitor
(AI) may respond to a second AI, usually of the steroidal type (e.
Women given the aromatase inhibitor
exemestane after surgery were 19% less likely to suffer metastatic, or spreading, cancer than those receiving standard treatment.
The International Aromatase Inhibitor
Expert Panel, which included 24 leading breast cancer clinicians from Europe, the USA, Australia, China and Brazil, agreed that with successful post-surgery treatment, patients with early breast cancer can potentially be cured of their condition and that AIs, such as anastrozole, should be prescribed as the preferred therapy(1).
Femara is a type of drug called an aromatase inhibitor
, which stops the natural production of oestrogen - the hormone that is responsible for the growth and recurrence of many breast cancers.