Vitamin K supplementation studies suggest that both forms of the vitamin contribute to protection from arterial calcification
in atherosclerosis, with a slight edge for vitamin [K.
Whereas low fetuin-A is associated with arterial calcification
and CVD events in ESRD (69), high fetuin-A has been associated with insulin resistance (21-23) and greater risk for diabetes (24, 25).
The third pattern of primary arterial calcification
would be a combination of the first two; that is, calcification of both the IEL and the media.
Other studies have suggested an association between the presence of calcified breast arteries and heart disease risk, he said, but this was the first to grade breast arterial calcification
Vitamin K in the treatment and prevention of osteoporosis and arterial calcification
However, correlation between cardiovascular risk factors, arterial calcification
, and bone tissue are inconsistent across studies.
CHICAGO -- Researchers have identified the threshold level of breast arterial calcification
that is associated with a 20% increased risk for coronary artery disease in women.
The prevalence of breast arterial calcification
is significantly lower among women who are on hormone replacement therapy, reported Dr.
Head of research Dr Julie Cox said: "Our findings suggest HRT reduces the risk of developing breast arterial calcification
and is beneficial in reducing the incidence of cardiovascular disease.
The company's pipeline programs consist of protein therapeutics for rare diseases with unmet medical need at various stages of development including the lead program, Kanuma(TM) (sebelipase alfa) for lysosomal acid lipase deficiency (LAL Deficiency), SBC-103 for mucopolysaccharidosis IIIB (MPS IIIB, also known as Sanfilippo B syndrome), and SBC-105 for generalized arterial calcification
of infancy (GACI) and other rare calcification diseases.
Tissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification
in warfarin-treated rats.
In rats fed a vitamin K-deficient diet, treatment with warfarin (a vitamin K antagonist) resulted in arterial calcification