asparaginase


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asparaginase

[‚as·pə′raj·ə‚nās]
(biochemistry)
An enzyme that catalyzes the hydrolysis of asparagine to asparaginic acid and ammonia.
References in periodicals archive ?
Strains which showed Rapid induction of asparaginase or best EAR were Used in a second screening: a fragment of sporulated Active mycelium of 6 mm of diameter was collected From the edge of colonies cultivated in Czapek-Dox (48 hours at 30[degrees]C) and transferred to the center of Czapek-Dox/BTB plates containing a hole of the Same size.
Different types of asparaginase can be used for different industrial and pharmaceutical purposes.
Asparaginase is an FDA approved drug for lymphoblastoid leukemia, and has never before been applied to treat GAS infections.
The researchers believe that this may be because of the asparaginase in the Capizzi regimen and because another chemotherapy drug, leucovorin, is used as a rescue therapy to help prevent common side effects associated with high doses of methotrexate (e.
DELFT, The Netherlands -- Frito-Lay and Procter & Gamble have reached an agreement with DSM Food Specialties here on the intellectual property rights to apply asparaginase in food products in order to reduce acrylamide levels, DSM said yesterday.
This is because they are unable to receive Asparaginase, a crucially important drug made only by a U.
The augmented BFM regimen popularized in trials of young children involves near-toxic doses of methotrexate, twice the usual doses of vincristine and steroids, and three times as much asparaginase as used in the standard BFM protocol.
These were acid and alkaline phosphatases (P cycling), arylsulfatase (S cycling), [Beta]-glucosidase (C cycling), and L- asparaginase (N cycling).
This approval underscores Shire's commitment to patients with acute lymphoblastic leukaemia through continued research and evolution of asparaginase therapy," said Howard B.
Tenders invited for Supply of Asparaginase activity assay kit
Besides its use in antitumor treatments, asparaginase is also employed in food technology to reduce the formation of acrylamide (a toxic carcinogenic compound) in fried and baked food (Kornbrust, Stringer, Lange, & Hendriksen, 2009; Zuo, Zhang, Jiang, & Mu, 2015; Kumar, Shimray, Indrani, & Manonmani, 2014; Batool, Makky, Jalal, & Yusoff, 2016).