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asparaginase |
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asparaginase [‚as·pə′raj·ə‚nās] (biochemistry) An enzyme that catalyzes the hydrolysis of asparagine to asparaginic acid and ammonia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Treatment protocols include the use of asparaginase, corticosteroids (prednisone and dexamethasone), an anthracycline (doxorubicin), mercaptopurine, methotrexate, and vincristine. Food and Drug Administration in February 1994 and is now indicated as a component of a multi-agent chemotherapeutic regimen for patients with acute lymphoblastic leukemia as up-front treatment in first-line therapy and for patients who have had hypersensitivity to asparaginase. During May, the FDA further limited the distribution of ONCASPAR to patients who are hypersensitive to other forms of L- asparaginase. |
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