astrocytoma

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astrocytoma

[‚as·trə‚sī′tōm·ə]
(medicine)
A slow-growing glial tumor made up of cells resembling astrocytes; often it will undergo malignant change and assume the appearance and growth characteristics of a glioblastoma.
References in periodicals archive ?
Diagnostic and prognostic role of Ki67 immunostaining in human astrocytomas using four different antibodies.
8) Other common lesions include retinal ("mulberry lesions") astrocytoma (50-75%), cardiac rhabdomyomas (50%), and pulmonary lymphangiomyomatosis (1-6% of women).
Nearly a dozen years ago, the 4-year-old Paul was diagnosed with an astrocytoma, the most common type of brain tumor.
Sievert and her colleagues at Children's Hospital were among several research groups who reported almost simultaneously in 2008 and 2009 that mutations in the BRAF gene were highly prevalent in astrocytomas in children.
GBM frequently arises de novo, but may develop from diffuse or anaplastic astrocytomas that undergo de-differentiation.
Currently, the most common molecular markers in neurooncology are 1p/19q codeletion in oligodendroglial tumors, mutations in the IDH1/2 genes in diffuse gliomas, hypermethylation of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter in glioblastomas and anaplastic gliomas, alterations in the EGFR and PTEN genes, and 10q deletions in GBMs, as well as BRAF alterations in pilocytic astrocytomas.
Vincristine therapy is the standard treatment approach for anaplastic astrocytomas and oligodendrogliomas (Levin, Silver, & Hannigan, 1990).
Astrocytomas are graded on the basis of cell growth and severity and grade 3 and grade 4 astrocytomas are collectively referred to as high-grade astrocytomas.
Most spinal cord neoplasms are glial tumors: astrocytomas (60%) and ependymomas (30%).
The present study was performed to determine the safety and efficacy of OPAXIO when it was added to standard therapy with radiation and temozolomide for unresectable high grade brain tumors (anaplastic astrocytomas (AA) and glioblastoma multiforme (GBM)).
Cerebellar astrocytomas of infancy (juvenile pilocytic astrocytoma) are thought to be curable with surgery.
These 5 genes represent different physiological pathways and may be regarded as universal reference genes applicable for accurate normalization of gene expression in human astrocytomas of different grades (WHO Grades II-IV) alone and compared with normal brain, thereby enabling longitudinally designed studies (e.