Objective: In the frame of this research program, carried out at the Institute of Molecular Sciences (ISM) within the University of Bordeaux (UB), we propose the development of new powerful Lewis acid catalysts for asymmetric synthesis
Despite major advances in organic synthesis predominantly over the past hundred years or so, asymmetric synthesis
of chiral organic compounds including the great majority of bioactive compounds, such as amino acids and their oligomers and polymers, i.
Specific topics include the redox isomerization of propargyl alcohols to enones, alkyne metathesis in organic synthesis, the catalytic enantioselective addition of terminal alkynes to carbonyls, the catalytic dimerization of alkynes, and the alkyne zipper reaction in asymmetric synthesis
2]octane) has been reported and named as Baylis-Hillman reaction and even a catalytic asymmetric synthesis
has been obtained from this reaction.
Synthesis of (2S)-(methanesulfonyloxy) Propanoyl Chloride, a Key Intermediate in the Asymmetric Synthesis
for his research in asymmetric synthesis
, development of new synthetic methods and total synthesis of complex natural products.
The first is on asymmetric synthesis
of heterocycles containing only one heteroatom and is organized into chapters according to the size of the ring: azirdine, azetideine, pyrrolidine, piperidine, azepine and larger rings.
Furthermore this effort shows the utility L-tartaric acid as a chiral controller in asymmetric synthesis
on carbohydrate templates: stereoselective Ugisynthesis of [alpha]-amino acid derivatives.
Dynamic Synthesis's custom synthesis services and products for pharmaceutical intermediates consist of three businesses, including Finorga SA, a manufacturer of advanced fine chemical intermediates and APIs, specializing in chiral technologies such as asymmetric synthesis
, enzyme resolution and multicolumn chromatography.
We will actively pursue new business and academic collaborations to capitalise on our distinctive expertise in unnatural amino acid technologies and asymmetric synthesis
With the advent of a strategy called asymmetric synthesis
, which uses new, lab-made chiral catalysts, chemists can now make any chiral chemical in an enantiomerically pure form.