atheroma


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atheroma

[‚ath·ə′rōm·ə]
(medicine)
A lipid deposit in the inner wall of an artery; characteristic of atherosclerosis.
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References in periodicals archive ?
Substantial regression of atheroma accompanied by 3.
Endothelial nitric oxide synthase exon 7 polymorphism, ischemic cerebrovascular disease, and carotid atheroma.
In the ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation) trial, investigators at 137 medical centers throughout North America and Europe used intravascular ultrasound to assess coronary atheroma volume in 910 patients with known coronary atherosclerosis.
In recently published ASTEROID (A Study to Evaluate the Effect of Rosuvastatin on Intravascular Ultrasound-Derived Coronary Atheroma Burden) trial, the effect of very high statin therapy (rosuvastatin 40 mg/day) on the regression of coronary atherosclerosis was evaluated by IVUS imaging (83).
A person is at high risk of developing atheroma if they smoke, have high blood pressure, a high blood-cholesterol level, are obese, are diabetic, or if they have a family history of heart attacks and angina.
Prof Dark said: "I have done more than 600 adult cardiac transplants and never before had a patient develop atheroma as rapidly as this.
2] is produced by the activated inflammatory cells within atheroma in situ, where enzyme expression is particularly high within the lipid core and co-localizes with apoptotic cells (17, 25).
Intravascular ultrasound performed at 18 weeks in 360 patients revealed that patients in the glimepiride group had highly significant progression of the primary efficacy parameter of mean change in percent atheroma volume (PAV) from baseline, of 0.
The patient group receiving active treatment met the secondary endpoints of regression of total (coronary) atheroma volume (TAV) and increases in Apolipoprotein A-I (ApoA-I) and HDL cholesterol.
Recording a verdict of accidental death, Warwickshire Coroner Michael Coker said a post mortem revealed Mr Jhita had suffered an atheroma which would have caused chest pains.