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atherosclerosis |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.03 sec. |
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atherosclerosis (ăth'ərōsklərō`sĭs): see arteriosclerosis arteriosclerosis (ärtĭr'ēōsklərō`sis) ..... Click the link for more information. . atherosclerosisor hardening of the arteriesChronic disease characterized by abnormal thickening of the walls of the arteries due to fatty deposits (atheromas) of cholesterol on the arterial inner walls (seeartery). These thicken, forming plaques that narrow the vessel channel (lumen) and impede blood flow. Scarring and calcification make the walls less elastic, raising blood pressure. Eventually plaques may completely block a lumen, or a blood clot (thrombus) may obstruct a narrowed channel. Atherosclerosis of one or more coronary arteries (also called coronary heart disease) can decrease the heart muscle's blood supply, causing angina pectoris. Complete blockage causes heart attack. In the brain, atherosclerosis may result in stroke. Treatments include drugs that reduce the level of cholesterol and fat in the blood, anticoagulants and other drugs that prevent the formation of blood clots, coronary bypass, and balloon angioplasty. |
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? Mentioned in | ? References in periodicals archive | |
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Women at high risk of stroke can be identified by the presence of calcified carotid artery atheromas on panoramic radiographs, investigators at the University of California, Los Angeles report. They were able to use radiolabeled annexin binding to apoptotic cells to show that therapeutic interventions, such as diet or drugs, reduce the numbers of dying macrophages in such atheromas and, therefore, may be useful in treating unstable plaque. |
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