asthma

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Related to atopic asthma: atopic dermatitis, intrinsic asthma

asthma

(ăz`mə, ăs`–), chronic inflammatory respiratory disease characterized by periodic attacks of wheezing, shortness of breath, and a tight feeling in the chest. A cough producing sticky mucus is symptomatic. The symptoms often appear to be caused by the body's reaction to a trigger such as an allergen (commonly pollen, house dust, animal dander: see allergyallergy,
hypersensitive reaction of the body tissues of certain individuals to certain substances that, in similar amounts and circumstances, are innocuous to other persons. Allergens, or allergy-causing substances, can be airborne substances (e.g.
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), certain drugs, an irritant (such as cigarette smoke or workplace chemicals), exercise, or emotional stress. These triggers can cause the asthmatic's lungslungs,
elastic organs used for breathing in vertebrate animals, excluding most fish, which use gills, and a few amphibian species that respire through the skin. The word is sometimes applied to the respiratory apparatus of lower animals.
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 to release chemicals that create inflammation of the bronchial lining, constriction, and bronchial spasms. If the effect on the bronchi becomes severe enough to impede exhalation, carbon dioxide can build up in the lungs and lead to unconsciousness and death. Following a steady 30-year decline, asthma deaths in the United States, especially among poor, inner-city blacks and among the elderly, began to rise from the late 1970s through the early 1990s. At the same time, the incidence of asthma also increased, both nationally and worldwide.

There is no cure for asthma. Although the disease may go through a period of quiescence, it appears that childhood asthmatics do not outgrow the disease as previously believed. Treatment includes inhaled or oral steroids or bronchodilators (albuterol, theophylline), breathing exercises, and, if possible, the identification and avoidance of triggers.

asthma

[′az·mə]
(medicine)
A pulmonary disease marked by labored breathing, wheezing, and coughing; cause may be emotional stress, chemical irritation, or exposure to an allergen.

asthma

a respiratory disorder, often of allergic origin, characterized by difficulty in breathing, wheezing, and a sense of constriction in the chest
References in periodicals archive ?
Each of the two probes of mononuclear cells from the BALF of individuals with atopic asthma (n=3) after segmental allergen provocation showed mRNA expression for IL-22 BP and IL-22.
This clinical study targeted 130 pediatric patients with mild to moderate atopic asthma, In this clinical research study, special Plasmacluster Ion generators producing an ion concentration of 100,000 ions/cm3 were set up in the home in two rooms where the subjects spent long periods of time selected from among the bedroom, living room, and children's room (nursery).
The second study demonstrates that all allergic or asthmatic associations in mothers are poor predictors of atopic asthma in their children; the descriptive statistics were low for all maternal factors.
2000) have shown only a weak protective effect against asthma itself, or they have shown a dual response in children with atopic asthma and allergy to be lower with increasing LPS exposure, and contrary to this, an increased prevalence of nonatopic wheeze with increasing LPS exposure (Braun-Fahrlander et al.
This receptor is central to the development of diagnostic methods, research tools, and most importantly, new therapies for atopic asthma, allergy and other IL-9 related diseases.
All the effects were dose-related and most strongly linked to pool attendance before the age of about 7 years, suggesting that attendance at indoor chlorinated pools, especially by young children, interacts with atopic status to promote the development of childhood atopic asthma.
Pearson and associates at the University of Nottingham (England) recruited 72 subjects with atopic asthma from the Nottingham Asthma Database.
Pearson and associates at the University of Nottingham (England) recruited 72 patients with atopic asthma from the Nottingham Asthma Database.
Allergen-mediated mast cell activation is an important mechanism in the pathogenesis of atopic asthma.
was shown in three recent studies in Europe to reduce exacerbations in atopic asthma patients on corticosteroids, even when the use of corticosteroids was significantly reduced.
Researchers studied 95 subjects between the ages of 14 and 16 years and divided them into four groups: those with active dermatitis (AD) with the presence of acute eczema; those with diagnosed AD but no symptoms for the last 2 years; those with diagnosed atopic asthma but with no symptoms at the time of the study; and healthy controls.