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asthma
(redirected from atopic asthma)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.
asthma (ăz`mə, ăs`–), chronic inflammatory respiratory disease characterized by periodic attacks of wheezing, shortness of breath, and a tight feeling in the chest. A cough producing sticky mucus is symptomatic. The symptoms often appear to be caused by the body's reaction to a trigger such as an allergen (commonly pollen, house dust, animal dander: see allergy allergy, hypersensitive reaction of the body tissues of certain individuals to certain substances that, in similar amounts and circumstances, are innocuous to other persons. Allergens, or allergy-causing substances, can be airborne substances (e.g.
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), certain drugs, an irritant (such as cigarette smoke or workplace chemicals), exercise, or emotional stress. These triggers can cause the asthmatic's lungs lungs, elastic organs used for breathing in vertebrate animals, excluding most fish, which use gills , and a few amphibian species that respire through the skin. The word is sometimes applied to the respiratory apparatus of lower animals.
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 to release chemicals that create inflammation of the bronchial lining, constriction, and bronchial spasms. If the effect on the bronchi becomes severe enough to impede exhalation, carbon dioxide can build up in the lungs and lead to unconsciousness and death. Following a steady 30-year decline, asthma deaths in the United States, especially among poor, inner-city blacks and among the elderly, began to rise from the late 1970s through the early 1990s. At the same time, the incidence of asthma also increased, both nationally and worldwide.

There is no cure for asthma. Although the disease may go through a period of quiescence, it appears that childhood asthmatics do not outgrow the disease as previously believed. Treatment includes inhaled or oral steroids or bronchodilators (albuterol, theophylline), breathing exercises, and, if possible, the identification and avoidance of triggers.


asthma

Chronic disease with attacks of shortness of breath, wheezing, and coughing from constriction and mucous-membrane swelling in the bronchi (air passageways in the lungs). It is caused primarily by allergy or respiratory infection. Secondhand smoke can cause asthma in children. Asthma is common and runs in families; predisposition may be hereditary. In established asthmatics, exercise, stress, and sudden changes in temperature or humidity can bring on attacks. Attacks usually last from a half hour to several hours; severe attacks can be fatal. Corticosteroids can control asthma; injections of epinephrine can relieve acute attacks. Prevention involves avoiding exposure to allergens.


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Cost-effectiveness analyses on both morbidity and atopic asthma have been conducted by Sullivan et al.
is a specialty pharmaceutical development company specializing in medications to prevent and treat atopic disease, including allergies, migraine headache, atopic asthma and dermatitis.
 
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