atropine


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atropine

(ăt`rəpēn, –pĭn), alkaloid drug derived from belladonnabelladonna
or deadly nightshade,
poisonous perennial plant, Atropa belladona, of the nightshade family. Native to Europe and now grown in the United States, the plant has reddish, bell-shaped flowers and shiny black berries.
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 and other plants of the family Solanaceae (nightshade family). Available either as the tincture or extract of belladonna, or as the pure substance atropine sulfate, it is a depressantdepressant,
any one of various substances that diminish functional activity, usually by depressing the nervous system. Barbiturates, sedatives, alcohol, and meprobamate are all depressants. Depressants have various modes of action and effects.
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 of the parasympathetic nervous systemnervous system,
network of specialized tissue that controls actions and reactions of the body and its adjustment to the environment. Virtually all members of the animal kingdom have at least a rudimentary nervous system.
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. It has some chemical similarity to the body substance acetylcholineacetylcholine
, a small organic molecule liberated at nerve endings as a neurotransmitter. It is particularly important in the stimulation of muscle tissue. The transmission of an impulse to the end of the nerve causes it to release neurotransmitter molecules onto the surface of
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 and interferes with nerve impulses transmitted by that substance. Atropine produces rapid heart rate, dilated pupils, dry skin, and anesthetizes the nerve endings in the skin. Because it relaxes smooth muscle and suppresses gland and mucous secretions, it has been used to treat peptic ulcer by reducing the production of stomach acid. Atropine is given before general anesthesia to keep the air passages clear and is an ingredient in various preparations for symptomatic relief of colds and asthma. It also acts as an antidote in poisoning from such agents as mushrooms, morphine, prussic acid, and nerve gas, but overdosage causes delirium, convulsions, and coma. A related alkaloid, scopolaminescopolamine
or hyoscine
, alkaloid drug obtained from plants of the nightshade family (Solanaceae), chiefly from henbane, Hyoscyamus niger. Structurally similar to the nerve substance acetylcholine, scopolamine acts by interfering with the transmission of nerve
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, is used mainly as a sedativesedative,
any of a variety of drugs that relieve anxiety. Most sedatives act as mild depressants of the nervous system, lessening general nervous activity or reducing the irritability or activity of a specific organ.
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.

atropine

[′a·trə‚pēn]
(pharmacology)
C17H23O3N An alkaloid extracted from Atropa belladonna and related plants of the family Solanaceae; used to relieve muscle spasms and pain, and to dilate the pupil of the eye.

atropine

, atropin
a poisonous alkaloid obtained from deadly nightshade, having an inhibitory action on the autonomic nervous system. It is used medicinally in pre-anaesthetic medication, to speed a slow heart rate, and as an emergency first-aid counter to exposure to chemical warfare nerve agents. Formula: C17H23NO3
References in periodicals archive ?
Effect of eserine, parathion, malathion, and atropine on density of TEBs and ABs of 21-day-old female Sprague-Dawley rat mammary glands (mean [+ or -] SE, n = 5) Treatment TEBs/[mm.
Success may be related to subject ethnicity and/or the technique to which it was being compared Pharmaceutical Anti-muscarinic drugs * Consistent data, inhibition of myopia shown when compared to placebos * Atropine found to be more effective than pirenzepine and cyclopentolate
So if you're short either diazepam or atropine, submit a requisition to your medical supply people.
Half were treated with atropine eye drops and half wore patches.
65) Therefore, ocular tissues traditionally thought not to have cholinergic innervation cannot be dismissed as potential sites of action of atropine in inhibiting the progression of myopia, as both neural and/or non-neural acetylcholine may be involved in ocular growth regulation.
Agutter, 48, was jailed in 1995 after lacing his wife Alex's gin and tonic with atropine - a form of Deadly Nightshade.
Antisecretory -- Robinul, Donnatal, Levsin, Atropine, scopolamine, Pamine, Quarzan, Tral, Darbid, Cantil, Banthine, Pro-Banthine, Pathilon, Bentyl, Daricon, Ditropan, various combination products
The anti-diarrhea product Donnagel cannot contain atropine sulfate, hyoscyamine sulfate, or scopolamine hydrobromide.
today announced that its collaborators at the University of Pittsburgh (Pitt) have completed a Phase I study at the University of Pittsburgh Medical Center with atropine sulfate delivered from the MicroDose proprietary dry powder inhaler (DPI).
2) Sometimes this takes the form of atropine sulphate eye drops instilled to the better eye to prevent this eye from accommodating, thereby ensuring that the weaker eye had to be relied upon during close work.
Given the similar structural formula of atropine to tiotropium, patients with a history of hypersensitivity reactions to atropine or its derivatives should be closely monitored for similar hypersensitivity reactions to SPIRIVA RESPIMAT.
Devoting 50 pages of her book to his death, Atasoy said the chemical expertise department of the ATK discovered that the chemical substances atropine and atenolol were found in different parts of Euzal's body including his liver, gallbladder, intestines and bone marrow.