autoantibody


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autoantibody

[¦ȯd·ō′ant·i‚bäd·ē]
(immunology)
An antibody formed by an individual against his own tissues; common in hemolytic anemias.
References in periodicals archive ?
As part of the partnership, Servier will advance ImmunoQure's therapeutic human Interferon-alpha autoantibody through preclinical development and into the clinic.
On the other hand, if specific autoantibodies and stage of microangiopathy reflect different processes in the disease, a combination of autoantibody status and NVC could be helpful for identifying patients at highest risk for cardiopulmonary involvement.
The authors of this study also created a panel of cardiac autoantibody assays to characterize post-myocardial infarction patients with type 1 diabetes.
Evaluating anti-SmD1-amino-acid 83-119 peptide autoantibody in children with other suspected autoimmune diseases
An important minority of prediabetic first-degree relatives of type 1 diabetic patients derives from seroconversion to persistent autoantibody positivity after 10 years of age.
2013, demonstrated that age, gender, and disease influence autoantibodies serum level in human and proposed that disease-induced perturbations in individual autoantibody profiles present an opportunity to detect accurately and diagnose diseases [20].
In children, a special type of AIHA and autoantibody occurs, which clinically results in paroxysmal cold hemoglobinuria (PCH), a condition where a sudden presence of hemoglobin in the patient's urine is noted, often associated with a viral illness.
A higher number of respiratory infections in the six months prior to islet autoantibody seroconversion was also associated with an increased HR.
As in the majority of adult studies, no one has reported any connection between autoantibody appearance and treatment outcome.
In contrast, intestinal biopsy shouldn't be recommended in asymptomatic screenpositive diabetes patients unless their tissue transglutaminase autoantibody level is high enough to confer a greater than 90% probability of a positive biopsy.