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autophagic vacuole

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autophagic vacuole [¦ȯd·ō¦fā·jik ′vak·yə·wōl]
(cell and molecular biology)
A membrane-bound cellular organelle that engulfs pieces of the substance of the cell itself. Also known as autolysosome.


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[FIGURE 6 OMITTED] Evaluation of mitochondrial mass and electron microscopy analysis Type II programmed cell death or autophagic cell death involves the accumulation of autophagic vacuoles (AV) in the cytoplasm of dying cells as well as enlargement of the mitochondrial mass.
2-8) Histopathologically, the identification of rimmed or autophagic vacuoles and tubulofilamentous inclusions, measuring 15 to 18 nm in diameter, in the background of inflammatory myopathic-appearing biopsy material are diagnostic of the entity.
 
 
 
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