autosome


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Related to autosome: hemophilia, autosomal inheritance

autosome

[′ȯd·ō‚sōm]
(genetics)
Any chromosome other than a sex chromosome.
References in periodicals archive ?
Translocations involving autosomes and the X chromosome with gonadal dysgenesis have been described by a few studies.
Potential paralogous contigs located on either chromosome 18 or chromosome 21 (target chromosomes) and alternative autosomes (reference chromosomes) were identified by sampling each target chromosome at 10-bp intervals in 100-bp segments.
The largest autosome is submetacentric and distinctly larger than the other chromosomes.
The nonhomology could involve different autosomes involved in the fusion events giving rise to neo-Y chromosomes in each species.
The present study revealed a rare de novo sex autosome translocation in a female with primary amenorrhea.
Note that Y chromosomes and mtDNA will show smaller Ne than autosomes because they are haploid (one copy per individual).
So extending the assumption of X chromosome evolution from autosome we can assume that paralog of X-linked genes must be on autosome and should be involved in the same disorder; like ARHGEF6 (X chromosome) has its paralog ARHGEF3 and ARHGEF4 on autosome; similarly NLGN3, NLGN4 on X -chromosome has paralog NLGN1 and NLGN2 on autosome.
The evolution of neo-xY1Y2 sex chromosome system by autosome sex chromosome fusion in Dundocoris nodulicarius Jacobs
hordei was determined, as well as in other Cecidomyiidae species that have been examined cytologically (White 1973), by a sex chromosome to autosome balance system with two X chromosomes.
A small percentage of these patients are SRY positive, meaning that they have cells to which the SRY gene was translocated to an X chromosome or autosome during parental meiosis.
The clones are assayed for autosomal meiotic nondisjunction by crossing clone-bearing females to males that carry a compound autosome (C(3)EN to screen 2L and C(2)EN to screen 3R).
This means that the mutant gene is located on an autosome rather than a sex chromosome, and males and females are equally affected when the mutant gene is present (Lashley, 1998).