auxotrophic mutant

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Related to auxotrophy: prototrophy, auxotrophs

auxotrophic mutant

[¦ȯk·sə¦trä·fik ′myüt·ənt]
(genetics)
An organism that requires a specific exogenous growth factor, such as an amino acid, for its growth.
References in periodicals archive ?
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1trial of CVD 1204 and CVD 1208.
Furthermore, a purine and pyrimidine metabolism, pathways for canonical amino acids, were identified, rendering auxotrophy an unlikely event (Siegl et al.
coli showed auxotrophy that can be suppressed by a rpoB mutation ([beta]T563P), which also suppresses the auxotrophy of a (p)ppGpp negative strain, called [(p)ppGpp.
aureus, confirmed by polymerase chain reaction amplification of the nuc and coa genes as well as by determination of the strain's auxotrophy for hemin.