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neuropathy
(redirected from axonal neuropathy)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.04 sec.

neuropathy

Disorder of the peripheral nervous system. It may be genetic or acquired, progress quickly or slowly, involve motor, sensory, and/or autonomic (see autonomic nervous system) nerves, and affect only certain nerves or all of them. It can cause pain or loss of sensation, weakness, paralysis, loss of reflexes, muscle atrophy, or, in autonomic neuropathies, disturbances of blood pressure, heart rate, or bladder and bowel control; impotence; and inability to focus the eyes. Some types damage the neuron itself, others the myelin sheath that insulates it. Examples include carpal tunnel syndrome, amyotrophic lateral sclerosis, poliomyelitis, and shingles. Causes include diseases (e.g., diabetes mellitus, leprosy, syphilis), injury, toxins, and vitamin deficiency (e.g., beriberi). See also neuralgia; neuritis.



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For a toxic axonal neuropathy, the lower extremities are likely to be more substantially affected than the upper extremities, although in this study some toxic effects were measured in both the upper and lower extremities.
99-94-1 Several residents were hospitalized with illness of unknown etiology characterized by fever, encephalitis, axonal neuropathy, and flaccid paralysis (unpublished data: Epi-1 report); increase in deaths of New York City birds, especially crows; human and bird tissue samples were positive for West Nile--like virus.
 
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