azathioprine


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Related to azathioprine: prednisone, methotrexate

azathioprine:

see metabolitemetabolite,
organic compound that is a starting material in, an intermediate in, or an end product of metabolism. Starting materials are substances, usually small and of simple structure, absorbed by the organism as food. These include the vitamins and essential amino acids.
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References in periodicals archive ?
Use of cyclosporine and azathioprine may account for low birth weight and prematurity15.
Immunosuppressive therapies such as steroids, azathioprine, and anti-tumor necrosis factor (anti-TNF) agents (infliximab and adalimumab) are usually required during the course of the disease, which predispose the host to life-threatening opportunistic infections.
To address conflicting data on whether azathioprine increases the risk of skin cancer, the authors con ducted the analysis of 27 studies (23 cohort studies, 1 randomized study, and 3 case-control studies) published between 1996 and 2011, which evaluated skin cancer risk associated with azathioprine in people who received an organ transplant from 1963 to 2011, at a median age of 38-54 years.
When should azathioprine be included to the patient's treatment regimen?
For the construction of this study, the medical bibliography was searched using the electronic databases of PUBMED, GUT and ECCO, with the use of the following keywords: azathioprine in Crohn's disease, toxicity and side effects.
Cyclosporin, methotrexate, oral corticosteroids, azathioprine,
Azathioprine is another cytotoxic agent used in sarciodosis treatment.
Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine.
Patients and methods Thirty five patients (group A) were given azathioprine pulse therapy (APT) which consisted of azathioprine 500 mg orally on 3 consecutive days and repeated every month.
Control group: no treatment control group (diabetic) daily cc 140 solution of fructose (10%) received group 1 to 4 (treatment of diabetes) after receiving the oral solution of fructose (10%) for 98 days, respectively, kg/bw mg/(3/5, 5/7, 15 and 21) received intra-peritoneal injection drug azathioprine.
For patients with more severe disease or in any patients when steroids could not be reduced to acceptable levels, immunosuppressive agents such as azathioprine, mycophenolate mofetil, and methotrexate were recommended.
Interim data from the study indicated that patients with idiopathic pulmonary fibrosis (IPF) who received a combined therapy of prednisone, azathioprine, and N-acetylcysteine (NAC) had no improvement in lung function, compared with a placebo group.