azidothymidine


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Related to azidothymidine: nevirapine

azidothymidine:

see AZTAZT
or zidovudine
, drug used to treat patients infected with the human immunodeficiency virus (HIV), which causes AIDS; also called azidothymidine. Originally developed in 1964 as an anticancer drug, AZT was never approved for that purpose.
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References in periodicals archive ?
4] Nonstandard abbreviations: mtDNA, mitochondrial DNA; AZT, azidothymidine; CS, citrate synthase; DTT, dithiothreitol; cpm, counts per minute; AZT-TP, azidothymidine triphosphate; and ddTTP, dideoxythymidine triphosphate.
Interim results from the study, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), demonstrate that a single oral dose of the antiretroviral drug nevirapine (NVP) given to an HIV-infected female in labor and another to her baby within 3 days of birth reduces the transmission rate by one-half compared with a similar short course of Azidothymidine (AZT).
146) Prenatal treatment with Azidothymidine (AZT) has been found to reduce the risk of fetal transmission to eight percent.
Epstein's account centers on azidothymidine (AZT), which in September 1986 was declared by a top U.
Zidovudine (Retrovir or azidothymidine [AZT]) was approved in March 1987 as the first antiviral therapy for HIV disease, when a clinical thai of ZDV versus placebo in patients with advanced disease was terminated early based on evidence of improved survival (Fischl, Richman, Grieco, et al.
For first-aid responders, this may include the HBV vaccination, gamma globulin injection, and azidothymidine (AZT) prophylaxis.
Richman DD, Fischl MA, Grieco MH, et al The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex.
Azidothymidine (AZT), the first drug shown to counteract the effects of HFV-1 infection, was previously known as a potential anticancer agent.
Antimicrobial: Antibacterial, antiviral, antifungal (gel), Antiviral, Acemannan acts alone and synergistically with azidothymidine (AZT)and acyclovir to block reproduction of Herpes and the AIDS virus [40,41,42], AntifungalAloe extract treatment of guinea pig feet that had been infected with Trichophyton mentagrophytes resulted in a 70% growth inhibition compared with untreated animals [43].
Yet the regular use of those drugs - such as zidovudine (also known as azidothymidine or AZT), protease inhibitors, and highly active antiretroviral therapy (HAART) involving multidrug therapies - has led to resistant HIV strains.
The first anti-HIV drug was AZT (also known as azidothymidine, zidovudine [ZDV], and Retrovir), which the Food and Drug Administration (FDA) approved in 1987 for treatment of AIDS, and in 1990 as a prophylactic in HIV positive people to delay the onset of AIDS.
Perinatal transmission is largely preventable through access to drugs such as azidothymidine (AZT), but these drugs and the necessary infrastructure for their delivery are out of reach for most African women.