beta-lactamase

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Related to b-lactamase: ESBL

beta-lactamase

[¦bād·ə ′lak·tə‚mās]
(microbiology)
A bacterial enzyme that catalyzes the hydrolysis of the lactam ring in some penicillin antibiotics, rendering them ineffective.
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Genotypes of TEM-type and CTX-M-type extended-spectrum b-Lactamases produced by E.
KEY WORDS: AmpC b-lactamase detection, Antimicrobial resistance, Multidrug resistant bacteria, Neonatal sepsis.
Extended-spectrum b-lactamases in the 21st century: Characterisation, epidemiology and detection of this important resistant threat.
Phenotypic detection of carbapenem susceptible metallo B-lactamase producing Gram negative bacilli in the clinical laboratory.
catarrhalis often produce an enzyme called B-lactamase that render many antibiotics, including amoxicillin, penicillin, and several cephalosporin antibiotics, inactive.
Objective: Fast detection of b-lactamase (bla) genes can minimize the spread of antibiotic resistance.
Carbapenem-resistant strain of Klebsiella oxytocaharboring carbapenem-hydrolyzing b-lactamase KPC-2.
Variations in the prevalence of strains expressing an extended-spectrum b-lactamase phenotype and characterization of isolates from Europe, the Americas, and the Western Pacific region.