beta-lactamase

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Related to b-lactamase: ESBL

beta-lactamase

[¦bād·ə ′lak·tə‚mās]
(microbiology)
A bacterial enzyme that catalyzes the hydrolysis of the lactam ring in some penicillin antibiotics, rendering them ineffective.
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References in periodicals archive ?
surveillance study has shown that up to 30% of Haemophilus influenzae strains are resistant to amoxicillin due to B-lactamase production.
Characterization of OXA-181, a carbapenem-hydrolyzing class D b-lactamase from Klebsiella pneumoniae.
Multidrug-resistant human and animal Salmonella Typhimurium isolates in France belong predominantly to a DT104 clone with the chromosome--and integron-encoded b-lactamase PSE-1.
Plasmid-mediated carbapenem-hydrolyzing b-lactamase, KPC-2, in Klebsiella pneumoniae isolates.
Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum B-lactamase encoded by an Escherichia coli integron gene.