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Inhibition of bacterial growth and metabolism.



complete inhibition of growth and propagation of bacteria; caused by unfavorable physical or chemical factors or by the absence of necessary conditions for their growth (moisture, temperature, pH of the medium, and so on). In these circumstances the metabolic processes of microbial cells are disrupted. When the effect of bacteriostatic factors ceases, growth and propagation of bacterial cells are resumed; if their effect is prolonged, the bacteria are destroyed. During bacteriostasis bacterial cultures usually lose their viability and stop producing toxic substances. The beneficial effect of chemotherapeutic medications used in both human and veterinary medicine is based on this phenomenon. Bacteriostasis may be caused by a great variety of bacteriostatic substances. Among the physical factors that cause bacteriostasis are radiation, low temperatures, and high osmotic pressure.


References in periodicals archive ?
Product Sterility Testing - Basic testing requirements and methods, isolator package validation requirements and Bacteriostasis and Fungistasis (B/F) requirements
Primary Pharmacological Actions II-8 Membrane Penetration II-8 Anti-Inflammation II-8 Antagonism to Platelet Aggregation II-8 Bacteriostasis II-8 Cholinesterase II-9 Diuresis II-9 Effect on Collagen II-9 Enhancement or Reduction of Concomitant Drug Action II-10 Enhancement of Cell Differentiation and Function II-10 Influence on Serum Cholesterol in Experimental Hypercholesterolemia II-10 Muscle Relaxation II-10 Membrane Transport II-10 Other Membrane Transport Studies II-11 Nerve Blockade (Analgesia) II-12 Nonspecific Enhancement of Resistance II-12 Protection against Ischemic Injury II-12 Vasodilation II-13 DMSO and PG/TX System II-13 DMSO Protects Cell Membrane II-13 DMSO Calcium and Hydroxyl Radicals II-13
It has achieved excellent test results in cytotoxicity, bacteriostasis, fungistasis, sterility and skin irritations studies.