Baculovirus

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Baculovirus

[‚bak·yə·lə′vī·rəs]
(virology)
A genus of invertebrate viruses that contains enveloped, double-stranded, supercoiled deoxyribonucleic, includes the subgroups nuclear polyhedrosis virus and granulosis virus.
References in periodicals archive ?
Major chapter topics include the history of the field, principles of epizootiology and microbial control, baculoviruses, RNA viruses that infect pest insects, fungal and bacterial entomophathogens, and nematode parasites and entomopathogens.
If we look a bit further ahead, there is an opportunity with future research to use baculoviruses as gene therapy vectors.
Scientists have discovered a gene that baculoviruses use to hijack gypsy moth caterpillars' brains.
In sections on DNA viruses, RNA viruses, and current topics, they discuss such matters as entomopoxviruses, the biology and genetics of nudiviruses, the genomics and biology of iflavilruses, cypoviruses, the role of microRNAs as regulators of host-virus interactions, apoptosis and humeral responses as antiviral responses in insects, and the ecology of baculoviruses.
Two naturally occurring baculoviruses (AgMNPV and HaSNPV)) are now used extensively to protect soybeans in Brazil and cotton in China.
Recombinant bacmids were then transfected into Sf9 cells (Riken Cell Bank, Ibaraki, Japan), and recombinant baculoviruses were isolated.
We fused 2 different baculoviruses (wild-type and recombinant) plus 2 influenza A viruses with color-coded microparticles and performed multiplexed fluorescence-activated cell-sorting (FACS) [3] titrations with specific antibodies and sera, and compared the results with results from ELISA.
Previous studies have shown the usefulness of BEI as an effective inactivating agent for Baculoviruses.
Such baculoviruses can be used to efficiently deliver genes to mammalian cells or organisms, and such genes can be expressed either from the baculovirus genome, or integrated into the mammalian cell genome, and can be used for expression of proteins such that purification of secreted or other protein products does not require removal of contaminating baculovirus particles or baculovirus envelope proteins.
Baculoviruses are rod-shaped DNA viruses, many of which begin their life cycle reproducing inside cells.
Under the terms of the agreement, SmithKline Beecham was granted a non-exclusive license to the recombinant HEV ORF2 capsid genes cloned into baculoviruses for commercial development, manufacturing, and marketing of HEV vaccines.
Safe, Simple, and High-capacity Gene Delivery into Insect and Vertebrate Cells by Recombinant Baculoviruses