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base excision repair |
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base excision repair [′bās ek′siz·zhən ri‚per]
(cell molecular) A deoxyribonucleic acid (DNA) repair system in which an altered base is removed from the sugar backbone by action of a specific DNA glycolase and then the abasic sugar is removed by apurinic/apyrimidic (AP) lyase and AP endonuclease, leaving a one-nucleotide gap that is then filled in and ligated. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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