base pairing


Also found in: Dictionary, Medical.
Related to base pairing: complementary base pairing

base pairing

[′bās ′per·iŋ]
(cell and molecular biology)
The hydrogen bonding of complementary purine and pyrimidine bases-adenine with thymine, guanine with cytosine-in double-stranded deoxyribonucleic acids or ribonucleic acids or in DNA/RNA hybrid molecules.
References in periodicals archive ?
Veglin is a potent antisense oligonucleotide which binds VEGF mRNA by Watson Crick base pairing, leading to mRNA degradation, and is the product of many years of fundamental research and product development work led by Dr.
Base pairing rules for DNA dictate that the hydrogen bonds work to join up appropriate nucleotide pairs like jigsaw pieces-adenine with thymine and cytosine with guanine.
Our model is that during this period when a single-strand region is bowed out, you could have base pairing between this upstream repeat and this downstream repeat to give you [a loop]," Wallace explains.