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beta blocker
(redirected from beta-adrenergic blocker)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.03 sec.
beta blocker [′bād·ə¦bläk·ər]
(neuroscience)
An adrenergic blocking agent capable of blocking nerve impulses to special sites (beta receptors) in the cerebellum; reduces the rate of heartbeats and the force of heart contractions.
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This presentation concluded that CK-1122534 increases the fractional shortening in ventricular myocytes (a measure of cardiac contractility) in a dose-dependent manner, does not increase the calcium transient, does not inhibit phosphodiesterase (PDE) activity and is active in the presence of a beta-adrenergic blocker.
Cytokinetics Presents Research Data from Heart Failure Program; ... by Business Wire
Furthermore, Cytokinetics presented results that demonstrated that CK-1122534 does not increase the calcium transient and does not inhibit phosphodiesterase activity and that the attendant increase in fractional shortening is not attenuated by the addition of a beta-adrenergic blocker, altogether providing evidence that CK-1122534 increases myocyte contractility by directly activating cardiac myosin.
Cytokinetics Announces Data from Heart Failure Drug Discovery Program ... by Business Wire
 
 
 
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