lactam

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Related to beta-lactam: beta-lactamase, Beta-lactam Ring

lactam

[′lak‚tam]
(organic chemistry)
An internal (cyclic) amide formed by heating gamma (γ) and delta (δ) amino acids; thus γ-aminobutyric acid readily forms γ-butyrolactam (pyrrolidone); many lactams have physiological activity.
References in periodicals archive ?
The hospital's EHR system generated a daily list of patients with a history of penicillin allergy who were on second-line options--vancomycin, daptomycin, aztreonam, linezolid, or moxifloxacin--for infections that would be better treated with beta-lactam antibiotics.
MRSA and related resistant bacteria can withstand a group of antibiotics called beta-lactams, which includes penicillin and methicillin.
These bacteria are resistant to beta-lactam antibiotics, such as methicillin, amoxicillin, penicillin, and oxacillin.
A recent study looked at whether additional community-associated MRSA coverage with trimethoprim-sulfamethoxazole in addition to beta-lactam therapy for cellulitis showed any benefit over therapy with only a beta-lactam (Clin.
The sample prep protocols incorporated into the MaxSignal Beta-Lactam ELISA Test Kit are inexpensive and fast, and offer high recovery rates.
Continuous infusion of beta-lactam antibiotics in severe sepsis: A multicenter double-blind, randomized controlled trial.
We have seen truly impressive bacterial eradication in highly resistant strains generated by combination of this beta-lactamase inhibitor with existing beta-lactam antibiotics," commented Christopher G.
The Enterome microbiome study, scheduled for completion in the second half of 2014, is expected to provide a better understanding of the harmful effects of beta-lactam antibiotics on the gut bacterial community.
In addition, later generations of beta-lactam antibiotics have broader spectrums of activity, which may obviate any benefit offered by adding aminoglycosides.
The acquisition includes Orchid's beta-lactam antibiotics manufacturing complex (comprising Cephalosporin, Penicillin and Carbapenem facilities), pharmaceutical research and development facility at Irungattukottai, Chennai and its generic injectable product portfolio and pipeline.
It is a common structural element of the penicillins, their synthetic and semi-synthetic derivatives, and other related molecules that constitute the broad family of drugs called the beta-lactam antibiotics.
The beta-lactam antibiotics tested are effective for the total elimination of Agrobacterium tumefaciens in indica rice calli (variety J-104), and do not interfere negatively in callus growth and plant regeneration.

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