beta-lactamase


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beta-lactamase

[¦bād·ə ′lak·tə‚mās]
(microbiology)
A bacterial enzyme that catalyzes the hydrolysis of the lactam ring in some penicillin antibiotics, rendering them ineffective.
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References in periodicals archive ?
Conclusion: This study shows a high frequency of Amp C beta-lactamase producing isolates from a hospital, which may lead to serious therapeutic problems.
In view of inadequate data regarding the incidence of these beta-lactamases in our region, we report these cases.
Prevalence of extended spectrum beta-lactamase producing Gram-negative bacteria in septicemic neonates in a tertiary care hospital.
Diversity and evolution of the class A chromosomal beta-lactamase gene in Klebsiella pneumoniae.
Phenotypic characteristics of clinical isolates of Klebsiella pneumoniae & evaluation of available phenotypic techniques for detection of extended spectrum beta-lactamases.
Meropenem is stable to hydrolysis by most beta-lactamases, including penicillinases and cephalosporinases produced by gram-negative and gram-positive bacteria, with the exception of carbapenem hydrolyzing beta-lactamases.
Countrywide spread of community and hospital-acquired extended-spectrum beta-lactamase (CTX-M-15)-producing Enterobacteriaceae in Lebanon.
Evaluation of extended spectrum beta-lactamase mediated resistance in Esche-richia coli and Klebsiella in urinary tract infection at a tertiary care hospital.
Table-II: Antibiotic resistance of AmpC beta-lactamase producing bacteria
1 Gram negative bacteria including Escherichia coli and Klebsiella pneumoniae produce resistance threat with the evolution of multiple resistance mechanisms like enzyme production resulting in extended spectrum beta-lactamases, Amp C b-lactamases and now the carbapenemases especially metallo-beta-lactamases (MBLs).
Antibiotic resistance rates of extended spectrum beta-lactamase producing Escherichia coli and Klebsiella spp.

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