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beta-lactamase

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
beta-lactamase [¦bād·ə ′lak·tə‚mās]
(microbiology)
A bacterial enzyme that catalyzes the hydrolysis of the lactam ring in some penicillin antibiotics, rendering them ineffective.


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Chromosome-encoded Ambler class A beta-lactamase of Kluyvera georgiana, a probable progenitor of a subgroup of CTX-M extended-spectrum beta-lactamases.
In vitro activity of ertapenem and other carbapenems against extended-spectrum beta-lactamase producing Escherichia coli and Klebsiella pneumoniae clinical isolates in a tertiary care center in Turkey.
The drug resistant E coli bacteria, known as Extended-Spectrum Beta-Lactamase (ESBL)-producing E coli, can cause urinary tract infections and blood poisoning.
 
 
 
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