tubulin

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tubulin

[′tü·byə·lən]
(biochemistry)
A globular protein containing two subunits; 10-14 molecules are arranged to form a microtubule.
References in periodicals archive ?
Alpha- and beta-tubulin are similar because they evolved by duplication and divergence from another ancestral gene.
Class III beta-tubulin isotype predicts response in advanced breast cancer patients randomly treated either with single-agent doxorubicin or docetaxel.
Beta-tubulin and benzimidazole resistance in the sheep nematode Haemonchus contortus.
Sequences of beta-tubulin cDNA from benzimidazole-susceptible and -resistant strains of Teladorsagia circumcincta, a nematode parasite of small ruminants.
Although leishmania parasites belong in the animal kingdom, Fong's team found that the amino acid sequence of leishmania beta-tubulin has more in common with plant tubulin sequences than with animal ones.
mexicana beta-tubulin but not to mammalian beta-tubulin.
Vincristine, paclitaxel and vinorelbine, which are widely used tubulin active agents, have clinically validated the concept of targeting beta-tubulin.
that binds to beta-tubulin, a known anti-cancer drug target.
T67 is an anti-cancer drug candidate with a novel chemical structure that binds to beta-tubulin, a known anti-cancer drug target.
Beta-tubulin is a cellular building block of microtubules and is essential to cell division.
15) Colchicine polymerizes microtubules by binding to beta-tubulins, a major constituent of microtubules.