betulinic acid


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betulinic acid

[¦bech·ə¦lin·ik ′as·əd]
(organic chemistry)
C30H48O3 A dibasic acid, slightly soluble in water, ethyl alcohol, and acetone.
References in periodicals archive ?
The result employing these tissues explants place the inhibition by betulinic acid at 69.
Several triterpenoids, including ursolic and oleanolic acid, betulinic acid, celastrol, pristimerin, lupeol, and avicins have been reported to possess anticancer activity (Petronelli et al.
Betulinic acid (5): Ethyl acetate solutions of combined major fractions "L", "M" and "N" (fractions 39-48) were pooled and evaporated to dryness to give a green residue ([congruente con] 4.
Isolation of betulinic acid and 23- dihydroxylean-12-en-28-oic acid from the leaves of Callistemon linearis.
Water stress (waterlog and drought) increase betulinic acid and phenolic compounds in Hypericumbrasiliense[7].
It is quite surprising that betulinic acid does not possess a dihydroxybenzene moiety, which is so prevalent in other tyrosinase inhibitors; for example, resveratrol has shown potent inhibitory effect on melanin synthesis via reduction in tyrosinase-related protein 2 among melanogenic enzymes.
Betulinic acid is a pentacyclic triterpenoid with reported antiretroviral, antimalarial and anti-inflammatory activity and anticancer properties extracted from the bark of Betula pubescens (53), (54).
Persimmons contain health benefiting phyto-nutrients flavonoid poly-phenolic anti-oxidants like catechins and gallocatechins as well as important anti-tumor compound betulinic acid.
Tshimankinda holds the patent "In vitro anti-sickling activity of betulinic acid, oleonolic acid and their derivatives" and was awarded the Diploma and medal of scientific merit of the Democratic Republic of Congo in 2010, the African Prize for Liberty and Development in 2009 and the Diploma of Honor and Merit as Best Congolese Professor in 2008.
The Changa fungi grows on birch trees in the northern stretches of Russia, and while scientists at Vector say that there are no solid tests linking the mushroom with combatting HIV, researchers said that the betulinic acid in the fungus is thought to be very toxic to cancers and other viruses.