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amine |
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amine (əmēn`, ăm`ēn): see under amino group amine. Amines are derivatives of the inorganic compound ammonia , NH3. When one, two, or all three of the hydrogens in ammonia are replaced by an alkyl or aryl group, the resulting compound is known as a primary, secondary, or tertiary amine, respectively. ..... Click the link for more information. . amineAny of a class of nitrogen-containing organic compounds derived, either in principle or in practice, from ammonia (NH3). Almost all their chemical names end in -ine. Replacement of one, two, or all three of the hydrogen atoms in ammonia with organic groups yields primary, secondary, or tertiary amines, respectively. Addition of a fourth hydrogen with an accompanying positive charge on the nitrogen atom results in a quaternary amine. Naturally occurring amines include alkaloids, present in certain plants; some neurotransmitters, including dopamine and epinephrine; and histamine. Industrially important amines include aniline, ethanolamine, and others, used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and in a host of other applications. A nitrogen atom with one or two hydrogens is often referred to as an amino group. amine an organic base formed by replacing one or more of the hydrogen atoms of ammonia by organic groups |
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These correlations, which indicate an increased dopamine metabolism, agree with recent experimental data in rats, showing that cadmium interferes with biogenic amine release from the hypothalamus, thereby inhibiting prolactin secretion (Lafuente et al. Cerebrospinal fluid biogenic amine metabolites in fibromyalgia/fibrositis syndrome and rheumatoid arthritis. Indeed, Rosin and Martin (1981) reported significant reductions in uptake of biogenic amine neurotransmitters into synaptosomes after exposure to Aroclor mixtures, whereas Mariussen and Fonnum (2001) recently reported that only noncoplanar PCB congeners inhibited uptake of labeled DA into striatal synaptosomes. |
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