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biological half-life

   Also found in: Dictionary/thesaurus, Medical, Financial, Wikipedia, Hutchinson 0.05 sec.
biological half-life [¦bī·ə¦läj·ə·kəl ′haf ‚līf]
(physiology)
The time required by the body to eliminate half of the amount of an administered substance through normal channels of elimination.


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This technology is designed to improve the stability, biological half-life and immunologic characteristics of therapeutic proteins naturally.
One of the earliest toxicokinetics studies reported that Pb, once absorbed into the blood compartment, has a mean biological half-life of about 40 days in adult males (Rabinowitz et al.
by pulmonary delivery, and to predictably extend the biological half-life of SCAs by PEGylation, further expands the clinical utility of SCA products beyond the range of monoclonal antibodies.
 
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