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blind passage

   Also found in: Dictionary/thesaurus, Medical, Legal, Wikipedia, Hutchinson 0.26 sec.
blind passage [′blīnd ′pasĀ·ij]
(microbiology)
Transfer of some material from an inoculated animal or cell culture that does not exhibit evidence of infection, to a fresh animal or cell culture.


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Two cultures (ArEq001 and ArEq003) showed CPEs on day 7 postinoculation of the original isolation; in the third culture (ArEq002), CPEs were observed only after the blind passage on day 7 after inoculation.
Cultures that was negative for virus growth by CPE after initial inoculation and one blind passage were then tested by PCR and Western blot.
 
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